All blog posts

.

This is a thematically organized list of all blog posts. Please check out the chronologically ordered list as well.

.

Electrophysiology

Hodgkin-Huxley model in current clamp and voltage clamp –
Simultaneous calcium imaging and extracellular recording from the same neuron
Discrepancies between calcium imaging and extracellular ephys recordings
The cell-attached soundtrack of calcium imaging – July
Whole-cell patch clamp, part 4: look and feel
Blue light-induced artifacts in glass pipette-based recording electrodes
Whole-cell patch clamp, part 3: Limitations of quantitative whole-cell voltage clamp
Whole-cell patch clamp, part 2: Line-frequency pick-up via the perfusion system
Whole-cell patch clamp, part 1: introductory reading

.

Microscopy

“Laser Scanners” by William Benner – November 15, 2022
Simple geometrical optics to understand and design point-scanning microscopes – May 28, 2022
Fast scanning, triplet states and photon yield – July 22, 2021
Heating up the objective for two-photon imaging – May 1, 2021
Interview with Bruno Pichler
Alignment tools
A practical guide for adaptive optics
Photon yield and pulse dispersion
Alvarez lenses and other strangely shaped optical elements
Springtime for two-photon microscopy
Can two-photon scanning be too fast?
All-optical entirely passive laser scanning with MHz rates
Matlab code for control of a resonant scanning microscope
Preamplifier bandwidth & two ways of counting photons
Fast z-scanning using a voice coil motor
Modulating laser intensity on multiple timescales (x, y and z)
Undistort/unwarp images for resonant scanning microscopy
Point spread functions
EODs for kHz imaging
A pockels cell with a broken crystal
Gain and photons per pixel
The excitation PSF in 2P point scanning

.

Calcium imaging

Self-supervised denoising of calcium imaging data – August 23, 2022
Video introduction to CASCADE – August 2, 2022
Large-scale calcium imaging & noise levels – October 4, 2021
5 reasons why to use Cascade for spike inference – August 9, 2021
Online spike rate inference with Cascade – May 13, 2021
Temporal dispersion of spike rates from deconvolved calcium imaging data – February
Simultaneous calcium imaging and extracellular recording from the same neuron
Discrepancies between calcium imaging and extracellular ephys recordings
Review: An artificial ground truth for calcium imaging – September
The cell-attached soundtrack of calcium imaging – July
How well do CNNs for spike detection generalize to unseen datasets?
How deconvolution of calcium data degrades with noise
A convolutional network to deconvolve calcium traces
Large field of view microscopes for mouse brain imaging

.

Paper discussions

Annual report of my intuition about the brain (2022) – December 31, 2022
Post-publication review: The geometry of robustness in spiking neural networks – October 9, 2022
Self-supervised denoising of calcium imaging data – August 23, 2022
Public peer review files – February 11, 2022
Post-publication review: Somato-dendritic coupling of L5 neurons in V1 – July
Post-publication review: Precise excitation-inhibition balance controls gain and timing in the hippocampus – June
Precise synaptic balance of excitation and inhibition
Genetically encoded voltage sensors
Some interesting 2-photon microscopy papers

.

Neuroscientific questions

Annual report of my intuition about the brain (2022) – December 31, 2022
Annual report of my intuition about the brain (2021) – December 31, 2021
Annual report of my intuition about the brain (2020) – January
Annual report of my intuition about the brain (2019)
Annual report of my intuition about the brain
Entanglement of temporal and spatial scales in the brain, but not in the mind
The crow as an animal model for neuroscience
Aphantasia
Finding the engram
A neuronal network of pointers
The unsolved problems of neuroscience
Odd opinions in neurobiology

.

Data analysis

Self-supervised denoising of calcium imaging data – August 23, 2022
Video introduction to CASCADE – August 2, 2022
5 reasons why to use Cascade for spike inference – August 9, 2021
Online spike rate inference with Cascade – May 13, 2021
Magic Matlab spells
The power of correlation functions
Spatial visualization of temporal components for neuronal activity imaging
A simple non-graphical user interface in Matlab: keyboard callback functions
Beyond correlation analysis: Dynamic causal modeling (DCM)
Beyond correlation analysis: Transfer entropy
Beyond correlation analysis: Granger causality
Beyond correlation analysis: incremental mutual information
Beyond correlation analysis: mutual information
Beyond correlation analysis
Beyond correlation analysis

.

Deep learning

Self-supervised denoising of calcium imaging data – August 23, 2022
Video introduction to CASCADE – August 2, 2022
5 reasons why to use Cascade for spike inference – August 9, 2021
Online spike rate inference with Cascade – May 13, 2021
Layer-wise decorrelation in deep-layered artificial neuronal networks
Understanding style transfer
The basis of feature spaces in deep networks
The most interesting machine learning AMAs on Reddit
Deep learning, part IV (2): Compressing the dynamic range in raw audio signals
Deep learning, part IV: Deep dreams of music, based on dilated causal convolutions
Deep learning, part III: understanding the black box
Deep learning, part II : frameworks & software
Deep learning, part I

.

Various other topics

Ambizione fellowship and an open PhD posiiton – October 28, 2022
Research and Intuition – June 12, 2021
Open access 3D electron microscopy datasets of brains
A list of cognitive biases
A short report from a Cold Spring Harbor lab course
The spikefinder dataset
Spike detection competition
Weblogs on circuit and cellular neuroscience
The larval zebrafish, and the adult zebrafish
Neuroscience on Youtube
Reglo ICC serial port control via Matlab
Colormaps (without colorspace theory)
Neuroengineering blogs