Monthly Archives: August 2017

All-optical entirely passive laser scanning with MHz rates

Is it possible to let a laser beam scan over an angle without moving any mechanical parts to deflect the beam? It is. One strategy is to use a very short-pulsed laser beam: A short pulse width means a finite … Continue reading

Posted in Calcium Imaging, Imaging, Microscopy | Tagged , , | 3 Comments

The most interesting machine learning AMAs on Reddit

It is very clear that Reddit is part of the rather wild zone of the internet. But especially for practical questions, Reddit can be very useful, and even more so for anything connected to the internet or computer technology, like machine … Continue reading

Posted in Data analysis, machine learning | Tagged , , , | Leave a comment

How deconvolution of calcium data degrades with noise

How does the noisiness of the recorded calcium data affect the performance of spiking-inferring deconvolution algorithms? I cannot offer a rigorous treatment of this question (Update August 2020: Now I have treated this question rigorously.) , but some intuitive examples. … Continue reading

Posted in Calcium Imaging, Data analysis, electrophysiology, Imaging, machine learning, Neuronal activity | Tagged , , , , | 1 Comment

A convolutional network to deconvolve calcium traces, living in an embedding space of statistical properties

As mentioned before (here and here), the spikefinder competition was set up earlier this year to compare algorithms that infer spiking probabilities from calcium imaging data. Together with Stephan Gerhard, a PostDoc in our lab, I submitted an algorithm based on convolutional networks. Looking … Continue reading

Posted in Calcium Imaging, Data analysis, electrophysiology, Imaging, machine learning, Neuronal activity | Tagged , , , , | 2 Comments