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Finding the engram
In their Nature Reviews|Neuroscience article, Finding the engram, Sheena Josselyn, Stefan Köhler and Paul Frankland discuss the recent developments, mainly in circuit neuroscience in mice, that contributed to finding memories on the cellular level, the so-called engram. They accumulate the evidence from … Continue reading
A simple non-graphical user interface in Matlab : keyboard callback functions
I’m not the first person to be annoyed by Matlabs guide (a tool used to generate GUIs that, unfortunately, are difficult to understand and painful to modify afterwards). Some months ago, I was looking for a way to implement a lightweight user interface for analyzing big … Continue reading
A network of pointers
When thinking about the way we think, it certainly makes sense to begin with a point which is also used by our thoughts as a starting point, which is sensual experience. To give an example, it is easy to imagine how a … Continue reading
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Tagged associative network, neuronal network, pointers, theoretical neuroscience
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The unsolved problems of neuroscience
The neuroskeptic blog recently mentioned a viewpoint paper which includes a list of the solved and unsolved problems of neuroscience. I’m probably not yet as deep into neuroscience as is the author of the paper, but I find it tempting to sharpen my … Continue reading
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Gain and photons per pixel
In 2010, Labrigger wrote about how to measure the gain of a imaging system. As mentioned there in the comments, this was discussed in more detail by James Pawley in the confocal microscopy mailing list quite recently (following a question I asked to the list), and I was … Continue reading
Colormaps (without colorspace theory)
The labrigger blog keeps posting links to all kind of colormaps, so I tried out some of them. Being partially colorblind, I do not like the default colormaps e.g. of Matlab. Here are some noisy data, with two different scalings … Continue reading
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The excitation PSF in 2P point scanning
For quite some time, I was unsure about the reasons why images degrade when going to deeper layers with 2P point scanning. This also has remained largely unclear to me until the present point, after having done the estimates presented … Continue reading
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Odd opinions in neurobiology
I have the impression that neurobiology is the single field in biology where many people with sometimes rather selective knowledge of the field have strong opinions about how it should work (i.e. how the brain should work). I don’t want to … Continue reading
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Genetically encoded voltage sensors
Genetically encoded calcium indicators (GECIs) are nowadays commonly used to report activity of many cells in transgenic animals; similarly, injected dyes like Rhod-2 can act as optical calcium reporters. The main shortcoming of this method is that it measures neuronal … Continue reading
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PhD at the FMI
In April, I started my PhD in neuroscience in the Friedrich lab at the FMI. Topic will be the investigation of brain areas for higher olfactory processing in the zebrafish, and I’ll be working with different physiological methods.
A blog about neurophysiology 