Some neuroscience blogs that do not focus on biological questions (here’s a list on circuit neuroscience blogs), but rather on technical hurdles of lab work and how to overcome them. Here, I’d like to point out some blogs that are to some extent incarnations of a spirit of DIY and costum-built solutions with an inclination for openness and willingness to share:
Labrigger is the most comprehensive and helpful blog on technical problems and solutions around neuroscience and neuroengineering, with a focus on two-photon microscopy. It is run by Spencer Smith from UCSB: http://labrigger.com/blog/
This blog, run by Dario Ringach from UCLA, covers technical aspects of resonant scanning 2P microscopy and is affiliated with Neurolabware, a 2P microscope vendor: https://scanbox.wordpress.com/
[Update 2017:] A blog by neuroscientist and “lab hacker” Bill Connelly from Australia National University: http://www.billconnelly.net/
[Update 2018:] A blog by neuroscientist Jakob Voigts, lab head in Janelia from 2022 on, and co-founder of the Open Ephys: http://jvoigts.scripts.mit.edu/blog/
[Update 2019:] A blog highlighting cheap and often open solutions for technical problems in the lab: http://www.labonthecheap.com/
[Update 2020:] The Neurowire blog powered by the company Scientifica for detailed and competent advice on everything about imaging and electrophysiology in neuroscience. Especially the #labhacks are very informative.
[Discontinued since March 2017:] Microscopy development summaries and some toy project descriptions, written by Kurt Thorn, who was running the Nikon microscopy facility at UCSF – he’s not a neuroscientist, but imaging methods are always relevant: http://nic.ucsf.edu/blog/