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Category Archives: Reviews
Interesting papers on behavioral timescale synaptic plasticity (experiments)
Behavioral timescale synaptic plasticity (BTSP) is a form of single-shot learning observed in hippocampal place cells in mice (Bittner et al., 2015, 2017). The idea is that post-synaptic activations (“eligibility traces”) are potentiated by a dendritic plateau potential/burst (“instructive signal”) … Continue reading
Interesting papers on recent neuroscience methods
Find below three interesting methods papers relevant for neuroscience. All three of them are, in my opinion, worth a quick read. Acoustic cameras to localize ultrasound vocalization of mice Sterling et al. (2023) from the lab of Bernhard Englitz addressed … Continue reading
Posted in Data analysis, Imaging, Microscopy, neuroscience, Reviews
Tagged Data analysis, Microscopy, photons
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The idea for a journal “eLife-A”
The process of publishing and reviewing scientific results is often a strange and difficult-to-navigate landscape. It would take too long to mention all the problems and pitfalls related to publishing. For example: overly high publication charges; long turnaround times for … Continue reading
Annual report of my intuition about the brain (2022)
How does the brain work and how can we understand it? To view this big question from a broad perspective at the end of each year, I’m reporting some of the thoughts about the brain that marked me most during … Continue reading
Post-publication review: The geometry of robustness in spiking neural networks
Selected paper: Calaim, Dehmelt, Gonçalves and Machens, The geometry of robustness in spiking neural networks, eLife (2022) The main message: This theoretical neuroscience paper describes an intuitive way how to think about the effect of single spikes in a network … Continue reading
Posted in Network analysis, Neuronal activity, Reviews
Tagged theoretical neuroscience
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Annual report of my intuition about the brain (2020)
How does the brain work and how can we understand it? I want to make it a habit to report some of the thoughts about the brain that marked me most during the past twelve month at the end of … Continue reading
Posted in Data analysis, machine learning, Network analysis, Neuronal activity, Reviews
Tagged complexity, deep learning, evolution, self-organization
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Discrepancies between calcium imaging and extracellular ephys recordings
To record the activity from a population of neurons, calcium imaging and extracellular recordings with small electrodes are the two most widely used methods that are still able to disentangle the contributions from single units. Here, I would like to … Continue reading
Review: An artificial ground truth for calcium imaging
Selected paper: Charles, Song, Tank et al., Neural Anatomy and Optical Microscopy Simulation (NAOMi) for evaluating calcium imaging methods, bioRxiv (2019). What is the paper about? Calcium imaging is a central method to observe neuronal activity in the brain of … Continue reading
Posted in Calcium Imaging, Data analysis, Imaging, Microscopy, Neuronal activity, Reviews
Tagged Data analysis, Microscopy, photons, PSF, Scanning
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Post-publication review: Somato-dendritic coupling of L5 neurons in V1
It requires more than a quick look at the abstract and the figures to fully understand a research paper and its limitations. One way to get there is to write a summary or critical review of a paper. In a contribution to … Continue reading
Posted in Calcium Imaging, electrophysiology, Microscopy, Reviews
Tagged Dendrites, electrophysiology, photons, theoretical neuroscience
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Post-publication review: “Precise excitation-inhibition balance controls gain and timing in the hippocampus”
It requires more than a quick look at the abstract and the figures to fully understand a research paper and its limitations. One way to go there is to write a summary or critical review of a paper. In a contribution to … Continue reading
A blog about neurophysiology 