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Author Archives: P.T.R. Rupprecht
Annual report of my intuition about the brain (2023)
How does the brain work and how can we understand it? To view this big question from a broad perspective, I’m reporting some ideas about the brain that marked me most during the past twelve months and that, on the … Continue reading
Posted in hippocampus, Neuronal activity, Review
Tagged evolution, language, theoretical neuroscience
9 Comments
Useful pieces from Twitter
Twitter used to be (and still is to some extent) a source of useful information for neuroscientists about technical details, clarifications of research findings and open discussions that cannot be obtained so easily otherwise. Here is a list of some … Continue reading
Posted in Data analysis, electrophysiology, Links, machine learning, Microscopy
Tagged Data analysis, electrophysiology, Microscopy
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Improving the resonant scanner’s sync signal using a phase locked loop (PLL)
Calcium imaging with two-photon point scanning is the technique to chronically record from identified neurons in the living brain of animals. The central piece of two-photon point scanning microscopes is a scan engine. This can be a complex optical device … Continue reading
Posted in Calcium Imaging, Imaging, Microscopy, neuroscience
Tagged Microscopy, photons, Scanning
6 Comments
Two random but interesting papers on neurophysiology with behavior
Bagur, Bourg et al. (2022) from the Bathellier Lab in Paris make the interesting finding that the auditory code is represented as temporal sequences of neuronal activity in early auditory processing stages and as spatial patterns in auditory cortex. I … Continue reading
Interesting papers on behavioral timescale synaptic plasticity (theory)
Behavioral timescale synaptic plasticity (BTSP) is a form of single-shot learning observed in hippocampal place cells in mice (Bittner et al., 2015, 2017). This finding is both interesting and inspiring for computational neuroscience for several reasons. In the first place, … Continue reading
Interesting papers on behavioral timescale synaptic plasticity (experiments)
Behavioral timescale synaptic plasticity (BTSP) is a form of single-shot learning observed in hippocampal place cells in mice (Bittner et al., 2015, 2017). The idea is that post-synaptic activations (“eligibility traces”) are potentiated by a dendritic plateau potential/burst (“instructive signal”) … Continue reading
Interesting papers on recent neuroscience methods
Find below three interesting methods papers relevant for neuroscience. All three of them are, in my opinion, worth a quick read. Acoustic cameras to localize ultrasound vocalization of mice Sterling et al. (2023) from the lab of Bernhard Englitz addressed … Continue reading
Posted in Data analysis, Imaging, Microscopy, neuroscience, Reviews
Tagged Data analysis, Microscopy, photons
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Interesting papers on online motion correction for calcium imaging
In a living animal, the brain is moving up and down in the skull. This brain motion can be due to breathing, heartbeat, tongue movements, but also due to changes of posture or running. For each brain region and posture, … Continue reading
Posted in Calcium Imaging, Data analysis, Imaging, machine learning, Microscopy, Neuronal activity, neuroscience
Tagged Calcium Imaging, Data analysis, Microscopy, photons, Scanning
4 Comments
The idea for a journal “eLife-A”
The process of publishing and reviewing scientific results is often a strange and difficult-to-navigate landscape. It would take too long to mention all the problems and pitfalls related to publishing. For example: overly high publication charges; long turnaround times for … Continue reading
Annual report of my intuition about the brain (2022)
How does the brain work and how can we understand it? To view this big question from a broad perspective at the end of each year, I’m reporting some of the thoughts about the brain that marked me most during … Continue reading
A blog about neurophysiology 